Dr. Michael Umkehrer
Lab Supervisor

Michael Umkehrer was born 1976 in Freising, Germany and studied chemistry at the Technical University of Munich. He earned his Diploma in December 2002 and joined Priaton in February 2003 as PhD student. His PhD-thesis dealt with the development of new multi-component reactions (MCRs) and was performed in a cooperation of Priaton and the Technical University of Munich. After his graduation in October 2004 he worked as a Senior Research Scientist at Priaton with emphasis on the optimization of pharmacological interesting MCRs and the development of new MCRs. Furthermore he was responsible for the liquid chromatography department, including analytical and preparative methods. Since January 2007 he holds additionally the position as lab supervisor.

List of publications

Umkehrer, M.; Ross, G.; Jäger, N.; Burdack, Ch.; Kolb, J.; Hu, H.; Alvim-Gaston, M.; Hulme, Ch.:Expeditious synthesis of Imidazo [1,2-c]pyrimidines via a [4+1]-cycloaddition
Tetrahedron Letters 2007, 48, 2213.

Kalinski, C.; Umkehrer, M.; Schmidt, J.; Ross, G.; Kolb, J.; Burdack C.; Hiller, W.; Hoffmann, St., D.: A novel One-pot Synthesis of highly diverse Indole Scaffolds by the Ugi-Heck Reaction
Tetrahedron Letters 2006, 47, 4683.

Kalinski, C.; Umkehrer, M.; Ross, G.; Kolb, J.; Burdack C.; Hiller, W.: Highly substituted Indol-2-ones, Quinoxalin-2-ones and Benzodiazepin-2,5-diones via a new Ugi(4CR)-Pd assisted N-Aryl Amidation Strategy
Tetrahedron Letters 2006, 47, 3423.

Umkehrer, M.; Kalinski, Kolb, J., Burdack C.: A new and versatile one-pot synthesis of Indol-2-ones by a novel Ugi-four-component-Heck reaction
Tetrahedron Letters 2006; 47, 2391.

Kalinski, C.; Umkehrer, M.; Gonnard, S.; Jäger, N.; Ross, G.; Hiller, W.: A new and versatile Ugi/SNAr Synthesis of Fused 4,5-Dihydrotetrazolo[1,5-a]quinoxalines:
Tetrahedron Letters 2006, 47, 2041.

Mayer, J., Umkehrer, M.; Kalinski, C., Ross, G., Kolb, J., Burdack C., Hiller, W.: New cleavable isocyanides for the combinatorial synthesis of α–amino acid analogue tetrazoles:
Tetrahedron Letters 2005, 46, 7393.

Umkehrer, M., Kolb, J., Burdack, C.; Hiller, W.: 2, 4, 5-Trisubstituted thiazole building blocks by a novel multi-component reaction.
Synlett 2005, 1, 79.

Umkehrer, M., Kolb, J., Burdack, C., Ross, G.; Hiller, W.: Synthesis of tetrazolopiperazine building blocks by a novel multi-component reaction:
Tetrahedron Letters 2004, 45, 6421.